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In this in-depth Q&A, Dr. Hamid Djalilian discusses his latest research on tinnitus, exploring the links between tinnitus and migraines, and various treatment approaches, including medication protocols and middle ear implants.
Hosted by Tinnitus Quest’s JD Hairston, a tinnitus patient and podcast host, the conversation covers the neurophysiological rationale behind Dr. Djalilian’s approaches, the significance of central sensitization in both migraines and tinnitus, and the promising potential of new treatment methods like CGRP antagonists and neuromodulation devices. The episode also delves into the complexities of securing research funding, the collaborative effort required for groundbreaking tinnitus research, and the importance of patient participation in comprehensive treatment protocols.
00:00 Introduction and Welcome
00:23 Host and Guest Backgrounds
01:18 Origins of Tinnitus Research
03:23 Understanding Tinnitus and Migraine Connection
04:00 Neurophysiological Insights
06:56 Central Sensitization and Tinnitus
15:51 Clinical Evidence and Studies
18:54 Migraine and Tinnitus Treatments
36:49 Challenges and Future Directions
50:38 Clinical Practice vs. Clinical Trials
51:52 Addressing Medication Concerns
52:31 Patented Formulation and Off-Label Use
55:35 Exploring CGRP Antagonists for Tinnitus
01:01:29 Balancing Risks and Benefits of Medications
01:04:14 The Role of Lifestyle Changes
01:08:14 Neuromodulation Devices and Future Treatments
01:12:12 Addressing Cost and Bias Concerns
01:26:49 Tracking Patient Outcomes
01:37:41 Challenges in Tinnitus Treatment
01:38:13 Understanding the Treatment Process
01:38:56 The Role of Patient Commitment
01:43:43 Exploring Middle Ear Implants
01:47:05 Mechanisms Behind Tinnitus and Treatment
01:51:43 Device Development and Clinical Trials
01:56:16 Funding and Collaboration in Tinnitus Research
02:09:51 Future Research Priorities
02:13:38 The Vision of Tinnitus Quest
02:20:15 Closing Remarks and Gratitude
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